Lpin1^fld

---

Species

Mus musculus

Symbol

Lpin1^fld

Category

allele

Allele of gene

Lpin1

Transgenic Constructs

None

Synonyms

• fld

Description

Three molecular changes have been identified in this allele. A 2 kb deletion encompasses exons 2 and 3 including the translation initiation sequence. An inversion exceeding 40 kb encompasses much of the coding region. An additional 0.5 kb sequence downstream of the inverted 40 kb has been duplicated and inserted in reverse orientation just upstream of this 40 kb inversion. Northern blots of adipose tissue extracts failed to detect mRNA from mice homozygous for this allele.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations