Foxe3^dyl

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Species

Mus musculus

Symbol

Foxe3^dyl

Category

allele

Allele of gene

Foxe3

Transgenic Constructs

None

Synonyms

• dyl

Description

Two missense mutations in the sequences encoding the forkhead domain were shown to co-segregate with the dyl phenotype: two C-to-T transitions at coding nucleotides 277 and 293 that change codons 93 and 98 from phenylalanine to leucine and serine respectively (p.F93L, p.F98S). These mutations are in a region of the protein thought to be critical for DNA binding.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations