Allele/Variant

Alox5tm1Fun

Species
Mus musculus
Symbol
Alox5tm1Fun
Category
allele
Allele of gene
Alox5
Transgenic Constructs
None
Synonyms
  • 5-LO KO
  • 5-LO-
Description
Insertion of a neomycin resistance cassette into exon 6 disrupted the Alox5 gene. RT-PCR studies did not detect transcript in resident peritoneal macrophages of homozygous mutant mice. Western blot analysis of resident peritoneal macrophages of homozygous mutant mice did not detect ALOX5.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations