Version: 8.0.0
Date: Tue Jan 28 2025
Il6tm1Kopf
MGI:1857197
Allele of Il6
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Il6tm1Kopf

Species
Mus musculus
Symbol
Il6tm1Kopf
Category
allele
Allele of gene
Il6
Transgenic Constructs
None
Synonyms
  • IL-6 KO
  • IL-6-
Description
A neomycin selection cassette was inserted into exon 2. RT-PCR experiments on RNA derived from LPS-stimulated macrophages of homozygous mice demonstrated that no detectable transcript was produced from this allele. ELISA and bioassay experiments confirmed that no functional protein was made in homozygous mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
No records match query. Try removing filters.
Showing 0 - 0 of 0 rows
per page

    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
    No records match query. Try removing filters.
    Showing 0 - 0 of 0 rows
    per page