Version: 8.0.0
Date: Tue Jan 28 2025
Nos1tm1Plh
MGI:1857227
Allele of Nos1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Nos1tm1Plh

Species
Mus musculus
Symbol
Nos1tm1Plh
Category
allele
Allele of gene
Nos1
Transgenic Constructs
None
Synonyms
  • alphaNOS1
  • Kn
Description
A neomycin cassette replaced exon 1. This exon encodes the initiation site and amino acids 1 - 159 of the protein. Northern blots of brain homogenates from homozygous mutant mice showed no detectable mRNA. Western blots of brain homogenates from homozygous mutant mice showed no detectable protein. However, splice variants are expressed and variable low levels of NOS activity are seen in the brain.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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