Syt1^tm1Sud

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Species

Mus musculus

Symbol

Syt1^tm1Sud

Category

allele

Allele of gene

Syt1

Transgenic Constructs

None

Synonyms

• Syt-

Description

A 5' portion of the exon encoding amino acids 270 through 308 and the preceding intron were replaced with a neomycin selection cassette. In addition to the coding sequence, the intron acceptor site was deleted. Lysates derived from the brains of homozygous mice were shown to contain less than 5% of the amount of a truncated form of the encoded protein compared to controls by immunoblotting.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations