Allele/Variant

Ccnd1tm1Wbg

Species
Mus musculus
Symbol
Ccnd1tm1Wbg
Category
allele
Allele of gene
Ccnd1
Transgenic Constructs
None
Synonyms
  • Ccnd11-3-
  • Ccnd1delta1-3
Description
A genomic fragment containing part of exon 1, exon 2 and exon 3 was replaced with a neomycin selection cassette. The deleted sequences encode the cyclin box domain thought to be required for protein activity. Western blot analysis on embryonic fibroblasts derived from homozygous mice confirmed that no stable protein was made from this allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations