Allele/Variant

Crhtm1Maj

Species
Mus musculus
Symbol
Crhtm1Maj
Category
allele
Allele of gene
Crh
Transgenic Constructs
None
Synonyms
  • CRH -
  • CRH KO
Description
The sequences encoding the pre-propeptide region were replaced by a neomycin resistance cassette. RT-PCR analysis demonstrated that the transcript was absent in whole brain RNA derived from homozygous mice. Immunohistochemical analysis demonstrated that the protein was not detectable in sections of the amygdala and cerebral cortex of brains of homozygous mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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