E2f1^tm1Meg

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Species

Mus musculus

Symbol

E2f1^tm1Meg

Category

allele

Allele of gene

E2f1

Transgenic Constructs

None

Synonyms

• E2F-1^-
• E2f1-

Description

Part of exon 3, intron 3 and exon 4 were replaced with a neomycin cassette. These sequences encode residues encoding the leucine zipper and those critical for DNA binding. Northern blot analysis did not detect a transcript made from this allele in fibroblasts isolated from homozygous embryos.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations