Bcl2^tm1Mpin

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Species

Mus musculus

Symbol

Bcl2^tm1Mpin

Category

allele

Allele of gene

Bcl2

Transgenic Constructs

None

Synonyms

• bcl-2 -

Description

Exon 2 was disrupted by the insertion of a lacZ gene and neomycin selection cassette. Western blot analysis on hippocampal lysates from homozygous mice demonstrated that no stable Bcl2 protein was made from this allele. A beta-galactosidase protein was produced from this allele under the control of the endogenous promoter.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations