Allele/Variant

Flt1tm1Jrt

Species
Mus musculus
Symbol
Flt1tm1Jrt
Category
allele
Allele of gene
Flt1
Transgenic Constructs
None
Synonyms
  • Flt-1-
  • Flt-1lacZ
Description
A LacZ-neomycin resistance cassette replaced sequences that encode the signal peptide. The authors predict this is a null allele because the translation start site is removed and reinitiation at the first two downstream Kozak sequences would result in out-of-frame translated products.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal blood circulation
MGI
abnormal blood vessel morphology
MGI
abnormal dorsal aorta morphology
MGI
abnormal embryo developmentMGI
abnormal embryonic erythrocyte morphologyMGI
abnormal heart development
MGI
abnormal physiological neovascularization
MGI
abnormal vascular development
MGI
abnormal visceral yolk sac blood island morphology
MGI
abnormal vitelline vasculature morphology
MGI
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Disease Associations

No data available