Version: 8.0.0
Date: Tue Jan 28 2025
Mettm1Cpo
MGI:1858019
Allele of Met
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Mettm1Cpo

Species
Mus musculus
Symbol
Mettm1Cpo
Category
allele
Allele of gene
Met
Transgenic Constructs
None
Synonyms
  • Met-
  • metd
Description
A mutant human cDNA coding for the transmembrane and cytoplasmic domain of the receptor was inserted in-frame into mouse genomic sequences. The cDNA was followed by a neomycin resistance cassette. A fusion protein consisting of the murine extracellular domain fused to the human transmembrane and cytoplasmic domain carrying the mutations Y1349F and Y1356Fis produced from this allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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