Allele/Variant

Vasptm1Mzim

Species
Mus musculus
Symbol
Vasptm1Mzim
Category
allele
Allele of gene
Vasp
Transgenic Constructs
None
Synonyms
  • VASP-KO
  • VASP-
Description
Exons 4 through 11 were replaced with a neomycin selection cassette. The deleted region encoded a proline-rich central domain and the proximal region of the EVH2 domain. Transcript was undetected in the spleens and large intestines of homozygous mutant mice. Immunoblot analysis using antibodies and antiserum raised against untargeted regions showed the absence of both normal and truncated protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations