Med1^tm1Jkr

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Species

Mus musculus

Symbol

Med1^tm1Jkr

Category

allele

Allele of gene

Med1

Transgenic Constructs

None

Synonyms

• PBP^-

Description

Exons 12-14 were disrupted with a PGK-neo cassette via homologous recombination resulting in the loss of 2 LXXLL motifs. Northern and Western blot analysis of fibroblasts from homozygous mutant embryos showed absence of gene transcript and protein product.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations