Version: 8.0.0
Date: Tue Jan 28 2025
Cd80tm1Shr
MGI:1861804
Allele of Cd80
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Cd80tm1Shr

Species
Mus musculus
Symbol
Cd80tm1Shr
Category
allele
Allele of gene
Cd80
Transgenic Constructs
None
Synonyms
  • B7-
  • B7-1-
Description
A neomycin selection cassette replaced the exon encoding the IgV-like domain of the protein. RT-PCR analysis on RNA derived from spleen, thymus and LPS-stimulated B cells of homozygous mice demonstrated that no detectable transcript was produced from this allele. FACS analysis on B cells derived from homozygous mice confirmed that no functional protein was encoded by this allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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