Gabrd^tm1Geh

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Species

Mus musculus

Symbol

Gabrd^tm1Geh

Category

allele

Allele of gene

Gabrd

Transgenic Constructs

None

Synonyms

• delta-
• delta⁰

Description

Insertion of a MC1-neomycin resistance cassette into exon 4 disrupted the gene. Northern blot analysis of cerebellar total RNA from homozygous mutant adult mice detected moderate levels of a novel 2.3kb transcript but not the 1.9kb wild-type transcript. Western blot analysis of cerebellar membranes did not detect the wild-type protein in homozygous mutant mice.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations