Map7^mshi

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Species

Mus musculus

Symbol

Map7^mshi

Category

allele

Allele of gene

Map7

Transgenic Constructs

None

Synonyms

None

Description

A large 13,080 bp deletion begins at nucleotide 1616 in intron 10 and extends to nucleotide 1959 in the 3' downstream sequence beyond exon 18. Exon 10 is then spliced to a cryptic "exon 11M" 4213 bp downstream of the deletion breakpoint. Exon 11M is, in turn, spliced to a second cryptic "exon 12M" located 830 bp downstream of exon 11M. The resulting 1724 nucleotide transcript is predicted to code for a 457 amino acid mutant protein.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations