Ncoa3^tm1Jxu

---

Species

Mus musculus

Symbol

Ncoa3^tm1Jxu

Category

allele

Allele of gene

Ncoa3

Transgenic Constructs

None

Synonyms

• AIB1^-
• SRC-3-

Description

A TGK-neomycin resistance cassette replaced sequences spanning exon 2 through exon 13. The cassette introduced a lacZ sequence in frame with the endogenous promoter. The authors predict that the targeted allele would not produce a functional protein, but would produce a beta-galactosidase fusion protein controlled by the endogenous promoter. Western analysis did not detect wild-type protein in lactating mammary glands of homozygous mutant mice.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations