Allele/Variant

Rargtm2Ipc

Species
Mus musculus
Symbol
Rargtm2Ipc
Category
allele
Allele of gene
Rarg
Transgenic Constructs
None
Synonyms
  • RARgamma2-
Description
A neomycin resistance cassette into exon 5 replaced part of the 5' untranslated region of the gene for the gamma2 isoform and the A2 region sequences up to the codon for amino acid 19 (nt 81-342). This disruption is predicted to selectively prevent the synthesis of the gamma2 isoform. RNase protection analysis of E10.5 embryos indicated that the mRNA encoding the gamma2 isoform was mutated in this allele, and that the wild-type transcript for the gamma1 isoform was transcribed.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
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