P2rx3^tm1Ckn

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Species

Mus musculus

Symbol

P2rx3^tm1Ckn

Category

allele

Allele of gene

P2rx3

Transgenic Constructs

None

Synonyms

• P2X3-

Description

Exon 1 was replaced with a neomycin resistance gene via homologous recombination, thus deleting the translation initiation codon. Protein product was absent from dorsal root ganglion, spinal cord, and peripheral tissues of homozygous mutant animals as shown by immunohistochemistry.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations