Allele/Variant

Fcer2atm1Putt

Species
Mus musculus
Symbol
Fcer2atm1Putt
Category
allele
Allele of gene
Fcer2a
Transgenic Constructs
None
Synonyms
  • CD23-
Description
A neomycin resistance cassette replaced 800 bp of the gene including part of exon 10, all of exon 11, and part of exon 12. The deleted sequences encode the carboxy-terminus, including the lectin homology domain with sequences that bind the C epsilon domain of IgE. Northern blot analysis of spleen did not detect transcript in homozygous mutant mice. Flow cytometric analysis did not detect protein on the surface of splenic B cells in homozygous mutant mice. Immunocytochemical analysis did not detect protein in asteroid dentritic cells near the corticomedullary junction of homozygous mutant thymus.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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