Agrn^Gt(Ex192)Byg

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Species

Mus musculus

Symbol

Agrn^Gt(Ex192)Byg

Category

allele

Allele of gene

Agrn

Transgenic Constructs

None

Synonyms

• Agrn^Beta-geo
• Agrn^{Gt(p1.8TM)192Wcs}

Description

Insertion of a gene trap construct, pGT1.8TM, into the gene between the two exons encoding the N-terminal seqences of the agrin isoforms. The insertion abolished activity of the long N-terminal basal laminae isoform (LN-agrin) but had no detectable affects on the short N-terminal cell associated isoform (SN-agrin).

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations