Allele/Variant

Pitx2tm2Jfm

Species
Mus musculus
Symbol
Pitx2tm2Jfm
Category
allele
Allele of gene
Pitx2
Transgenic Constructs
None
Synonyms
  • delta abhypoc
  • Pitx2PZNeo
Description
An IRES-lacZ cassette followed by a loxP-flanked neomycin resistance cassette replaced a genomic fragment containing the coding region of exon 2 and all of exon 3. This allele encodes the heart- and lung-specific c isoform in the absence of the a and b isoforms. The presence of the retained neomycin resistance cassette results in a hypomorphic allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations