Rxra^tm3Ipc

---

Species

Mus musculus

Symbol

Rxra^tm3Ipc

Category

allele

Allele of gene

Rxra

Transgenic Constructs

None

Synonyms

• HS23.26Cre
• RXRalpha af1

Description

Deletion of exon 2 (with the exception of its splicing acceptor site), intron 2, and 102 bp of exon 3. The resulting protein is truncated from amino acid 11-132l. This region contains the autonomous AF-1 activation function and several phosphorylation sites. This is a null mutation for the alpha 2 and 3 isoforms.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations