Version: 8.0.0
Date: Tue Jan 28 2025
Irs1tm1Tka
MGI:2136643
Allele of Irs1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Irs1tm1Tka

Species
Mus musculus
Symbol
Irs1tm1Tka
Category
allele
Allele of gene
Irs1
Transgenic Constructs
None
Synonyms
  • IRS-1-
Description
A PGK-neomycin cassette disrupted the first exon of the gene, preventing the production of stable mRNA transcripts. No transcript was detected in hepatic tissues of homozygous null mice by Northern blot analysis. Western blots of liver homogenates showed no detectable protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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