Version: 8.0.0
Date: Tue Jan 28 2025
Nos3tm1Plh
MGI:2150145
Allele of Nos3
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Nos3tm1Plh

Species
Mus musculus
Symbol
Nos3tm1Plh
Category
allele
Allele of gene
Nos3
Transgenic Constructs
None
Synonyms
  • eNOS KO
  • eNOS-
Description
A neomycin cassette replaced 3 exons that encode the NADPH ribose and adenine binding sites of the protein (amino acids 1010 - 1144). Western blots of protein extracts of brain, heart, lung, and aorta/vena cava from homozygous mutant mice showed no detectable encoded protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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