Version: 8.0.0
Date: Tue Jan 28 2025
Gnai2tm1Lbi
MGI:2152603
Allele of Gnai2
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Gnai2tm1Lbi

Species
Mus musculus
Symbol
Gnai2tm1Lbi
Category
allele
Allele of gene
Gnai2
Transgenic Constructs
None
Synonyms
  • alphai2-
  • Gai2-
Description
A neomycin resistance cassette was inserted into exon 3. The truncated protein is predicted to be inactive and also lack the cysteine at position 352 which is ADP-ribosylated by pertussis toxin. No protein was detected in homogenates from homozygous mice by ADP-ribosylation with pertussis toxin. The absence of protein was also confirmed by immunoblotting.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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