Allele/Variant

Adora3tm1Jbsn

Species
Mus musculus
Symbol
Adora3tm1Jbsn
Category
allele
Allele of gene
Adora3
Transgenic Constructs
None
Synonyms
  • A3-
  • A3AR-
Description
A neomycin selection cassette replaced a genomic fragment containing the initiation codon through sequences encoding the third transmembrane domain and the following intron. No transcript was detectable in northern blot analysis on RNA from bone marrow-derived mast cells (BMMCs) derived from homozygous mice. Binding assays confirmed the absence of protein from BMMCs derived from homozygous mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations