Adora3^tm1Jbsn

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Species

Mus musculus

Symbol

Adora3^tm1Jbsn

Category

allele

Allele of gene

Adora3

Transgenic Constructs

None

Synonyms

• A3^-
• A3AR-

Show All 4

Description

A neomycin selection cassette replaced a genomic fragment containing the initiation codon through sequences encoding the third transmembrane domain and the following intron. No transcript was detectable in northern blot analysis on RNA from bone marrow-derived mast cells (BMMCs) derived from homozygous mice. Binding assays confirmed the absence of protein from BMMCs derived from homozygous mice.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations