Version: 8.0.0
Date: Tue Jan 28 2025
H2-Aab-tm1Blt
MGI:2157977
Allele of H2-Aa
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

H2-Aab-tm1Blt

Species
Mus musculus
Symbol
H2-Aab-tm1Blt
Category
allele
Allele of gene
H2-Aa
Transgenic Constructs
None
Synonyms
  • Aa0
  • Aalpha-
Description
Insertion of a PGK-neomycin resistance cassette into exon 2, which encodes the alpha-1 domain of the A-alpha chain, disrupted the gene. Cytofluorometric analyses of lymphocytes from thymus and lymph nodes did not detect expression of the A-alphaA-beta heterodimer in homozygous mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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