Allele/Variant

B4galnt1tm1Sia

Species
Mus musculus
Symbol
B4galnt1tm1Sia
Category
allele
Allele of gene
B4galnt1
Transgenic Constructs
None
Synonyms
  • GalNAcT-
  • GM2s-KO
Description
A neomycin selection cassette was inserted into exon 4. TLC analysis demonstrated that GM2 or complex gangliosides were absent in the liver and brain of homozygous mice, and enzyme activity assays in liver and brain of homozygous mice confirmed that no functional protein was made from this allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations