Version: 8.0.0
Date: Tue Jan 28 2025
Apoetm3(APOE*4)Mae
MGI:2158398
Allele of Apoe
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Apoetm3(APOE*4)Mae

Species
Mus musculus
Symbol
Apoetm3(APOE*4)Mae
Category
allele
Allele of gene
Apoe
Transgenic Constructs
Synonyms
  • 4
  • APOE*4
Description
A DNA fragment containing exons 2-4 of the human APOE gene (the APOE4 isoform) replaced an equivalent portion of the mouse Apoe gene. Western blot analysis on plasma derived from homozygous mice demonstrated that the human protein was expressed from this allele and the endogenous mouse protein was not detectable.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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