Version: 8.0.0
Date: Tue Jan 28 2025
H2-Ab1b-tm1Gru
MGI:2158420
Allele of H2-Ab1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

H2-Ab1b-tm1Gru

Species
Mus musculus
Symbol
H2-Ab1b-tm1Gru
Category
allele
Allele of gene
H2-Ab1
Transgenic Constructs
None
Synonyms
  • [KO]Abb
  • Abbeta-
Description
A neomycin selection cassette was inserted into exon 2. In addition, the ES cell line used was derived from the 129S2/SvPas strain, which carries a deletion in the promoter region of H2-Ea. Consequently, these MHC class II molecule-deficient mice lacked cell surface expression of both class II-A and class II-E MHC proteins.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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