Cfb^tm1Mbo

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Species

Mus musculus

Symbol

Cfb^tm1Mbo

Category

allele

Allele of gene

Cfb

Transgenic Constructs

None

Synonyms

• B/C2^-
• Bf/C2^-

Show All 4

Description

A 6 kb genomic fragment containing part of exon 1 through exon 18 was replaced with a promoterless lacZ gene linked to a neomycin selection cassette. Northern blot analysis on liver RNA derived from homozygous mice demonstrated that no detectable transcript was produced from this allele. Activity assays on serum derived from homozygous mice confirmed that no functional protein was made.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations