Allele/Variant

Chrna9tm1Bedv

Species
Mus musculus
Symbol
Chrna9tm1Bedv
Category
allele
Allele of gene
Chrna9
Transgenic Constructs
None
Synonyms
  • alpha9 knockout
  • alpha9-
Description
Exon 4 and flanking intronic sequences were replaced with a neomycin selection cassette. The deleted sequences encode the ligand-binding site and the first two transmembrane domains. RT-PCR analysis on nasal epithelium derived from homozygous mice confirmed that no detectable transcript containg sequences from exon 4 is produced from this allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal cochlear IHC efferent innervation patternMGI
abnormal cochlear nerve compound action potentialMGI
abnormal cochlear OHC efferent innervation patternMGI
abnormal cochlear outer hair cell physiology
MGI
abnormal distortion product otoacoustic emissionMGI
abnormal sensory neuron innervation patternMGI
Showing 1 - 6 of 6 rows
per page

Disease Associations

No data available