Allele/Variant

Thbdtm1Wlr

Species
Mus musculus
Symbol
Thbdtm1Wlr
Category
allele
Allele of gene
Thbd
Transgenic Constructs
None
Synonyms
  • ThbdPro
  • TMP
Description
Point mutations were introduced into the gene that altered codon 387 from one encoding glutamate to one endcoding proline. A neomycin selection cassette was also inserted downstream of the polyadenylation site in the 3' end of the gene. Immunohistochemistry experiments confirmed that a mutant protein was expressed from this allele in an identical pattern to the wild-type protein (data not shown).
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations