Version: 8.0.0
Date: Tue Jan 28 2025
Portm1Cbk
MGI:2159651
Allele of Por
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Portm1Cbk

Species
Mus musculus
Symbol
Portm1Cbk
Category
allele
Allele of gene
Por
Transgenic Constructs
None
Synonyms
  • CYPOR-
  • delta56
Description
A neomycin resistance gene replaces 2.5 kb of intron 1 and all but the last 6 bp of exon 2. This allele deletes the sequences encoding the translation start site as well as the membrane-binding domain. The targeting event generated a truncated protein which localized to the cytoplasm and not present in microsomes. Cytochrome c reductase activity in liver microsomes isolated from adult heterozygous mice was 50% that found in wild-type mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
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