Version: 8.0.0
Date: Tue Jan 28 2025
Speer6-ps1Tg(Alb-cre)21Mgn
MGI:2176228
Allele of Speer6-ps1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Speer6-ps1Tg(Alb-cre)21Mgn

Species
Mus musculus
Symbol
Speer6-ps1Tg(Alb-cre)21Mgn
Category
allele
Allele of gene
Speer6-ps1
Transgenic Constructs
Synonyms
  • Alb-cre
  • Alb-Cre
Description
The transgene contains a 2.34 kb mouse albumin enhancer/promoter (M. Magnuson verified mouse promoter, personal communication), a nuclear localization sequence-modified Cre recombinase gene and a 2.1 kb fragment from the human growth hormone gene. The promoter is active in hepatocyte cells of the liver. 7 copies of the transgene are estimated to be present. Line 21 inserted into the gene at 3172116-3172120 (Build GRCm38/mm10) resulting in a 4 bp deletion. Founder line x has a copy number of approximately 10.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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