Tg(CAG-cat,-lacZ)11Miya

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Species

Mus musculus

Symbol

Tg(CAG-cat,-lacZ)11Miya

Category

allele

Allele of gene

None

Transgenic Constructs

None

Synonyms

• CAG-CAT-Z
• CAG-CAT-Z11

Show All 4

Description

This allele is used to detect transient expression of Cre recombinase. The transgene carries a lacZ gene downstream of a CMV enhancer and chicken beta-actin promoter and a floxed chloramphenicol acetyltransferase gene (a stuffer sequence). Upon Cre-mediated excision of the stuffer sequence, the modified allele expresses lacZ in tissues where Cre is expressed. The authors state that a single copy of the transgene was inserted and expression was observed throughout all embryonic and adult stages.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations