Allele/Variant

Ptpn1tm1Bpk

Species
Mus musculus
Symbol
Ptpn1tm1Bpk
Category
allele
Allele of gene
Ptpn1
Transgenic Constructs
None
Synonyms
  • PTP-1B -
  • PTP1B-KO
Description
A neomycin selection cassette replaced a genomic fragment containing exons 5 and 6, which contain sequences encoding the tyrosine phospahatase active site. Western blot analysis on liver microsomes derived from homozygous mice confirmed that no detectable protein was expressed from this allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations