Allele/Variant

Egftm1Dle

Species
Mus musculus
Symbol
Egftm1Dle
Category
allele
Allele of gene
Egf
Transgenic Constructs
None
Synonyms
None
Description
A neomycin resistance cassette replaced a genomic fragment containing exon 20, which encodes the first two disulfide loops. Northern blot analysis on RNA derived from salivary gland and kidney of homozygous mice demonstrated that negligible amounts of transcipt is produced from this allele. Western blot analysis on samples derived from salivary gland of homozygous mice confirmed that no detectable protein is expressed from this allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations