Brca2^tm1Cbl

---

Species

Mus musculus

Symbol

Brca2^tm1Cbl

Category

allele

Allele of gene

Brca2

Transgenic Constructs

None

Synonyms

• Brca2^Tr2014

Description

A neomycin selection cassette was inserted into exon 11 at position 6038. RT-PCR analysis on RNA derived from homozygous animals demonstrated that a partial transcript is made from this allele. Western blot analysis confirmed that no protein with an intact carboxy-terminus was expressed from this allele, but the authors do not rule out the possiblilty that a partial product could be made.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations