Allele/Variant

Col1a1tm2.1Bst

Species
Mus musculus
Symbol
Col1a1tm2.1Bst
Category
allele
Allele of gene
Col1a1
Transgenic Constructs
None
Synonyms
  • exon 2delta
Description
A floxed PGK-neomycin resistance cassette deleted exon 2 and placed a silent mutation in exon 7. Cre-mediated recombination in vivo removed the neo cassette in the germ line. The authors predict that this allele would produce a correctly spliced protein that lacks 65 amino acids, almost the entire globular domain of the N-propeptide.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations