Version: 8.0.0
Date: Tue Jan 28 2025
Grin2btm2Mim
MGI:2179059
Allele of Grin2b
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Grin2btm2Mim

Species
Mus musculus
Symbol
Grin2btm2Mim
Category
allele
Allele of gene
Grin2b
Transgenic Constructs
None
Synonyms
  • GluRepsilon2dC
Description
A termination codon and a neomycin selection cassette were replaced 0.9 kb of the sequences following codon 997. RNAase protection assays on RNA derived from brain of homozyous mice demonstrated that normal levels of a mutant transcript are produced from this allele. Western blot analysis on whole brain lysates confirmed that a truncated protein is expressed from this allele in homozygous mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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