Chrna6^tm1Nchx

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Species

Mus musculus

Symbol

Chrna6^tm1Nchx

Category

allele

Allele of gene

Chrna6

Transgenic Constructs

None

Synonyms

• alpha6-

Description

A 4 kb region of this gene including exons 1 and 2 was replaced with a neomycin cassette via homologous recombination, resulting in the deletion of sequences encoding the translation initiation codon, signal peptide, and part of the N-terminal extracellular domain. In situ hybridization did not detect mRNA in retinal ganglion cells from brain of homozygous mutant animals.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations