Version: 8.0.0
Date: Tue Jan 28 2025
Erbb2tm1Mul
MGI:2179176
Allele of Erbb2
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Erbb2tm1Mul

Species
Mus musculus
Symbol
Erbb2tm1Mul
Category
allele
Allele of gene
Erbb2
Transgenic Constructs
None
Synonyms
  • erbB-2KD
Description
Exon 1 was targeted with a PGK-neo cassette preceded by a point mutation at lysine 757 (K757M) destroying the kinase activity of the gene product. Homozygous mutant embyros were identified by genotype analysis at E11.5-E13.5.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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