Allele/Variant

Top2btm1Jcw

Species
Mus musculus
Symbol
Top2btm1Jcw
Category
allele
Allele of gene
Top2b
Transgenic Constructs
None
Synonyms
  • top2beta -/-
  • top2betadelta1
Description
Two exons of the endogenous locus, one of which contains the active-site tyrosine codon, were replaced by a neo cassette. No transcript was detected from the liver of E18.5 mutant embryos. No protein was detected in extracts from fibroblasts of E13.5 mutant embryos.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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