Poll^tm1Crey

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Species

Mus musculus

Symbol

Poll^tm1Crey

Category

allele

Allele of gene

Poll

Transgenic Constructs

None

Synonyms

• pol lambda-

Description

Exons 5-7 were replaced with a neomycin resistance gene via homologous recombination resulting in the loss of the DNA polymerase catalytic site and HhH domain. RT-PCR of spleen B cells from homozygous mutant animals failed to detect gene expression.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations