Asic1^tm1Wsh

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Species

Mus musculus

Symbol

Asic1^tm1Wsh

Category

allele

Allele of gene

Asic1

Transgenic Constructs

None

Synonyms

• ASIC^-
• ASIC1^-

Show All 3

Description

Exon 1 of this gene was replaced with a PGK-neo cassette via homologous recombination resulting in the deletion of the first 121 amino acids, which includes the intracellular N terminus, the first transmembrane domain, and a portion of the extracellular domain. Immunoprecipitation and Western blot analysis failed to detect protein in extracts from brain and hippocampus of homozygous mutant animals.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations