Xrcc6^tm1Fwa

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Species

Mus musculus

Symbol

Xrcc6^tm1Fwa

Category

allele

Allele of gene

Xrcc6

Transgenic Constructs

None

Synonyms

• Ku70-
• Ku70DKO

Description

450 bp of this gene encompassing exon 4 and part of exon 5 were replaced with a neo cassette via homologous recombination resulting in a shift in the reading frame and predicted protein truncation after the first 64 residues. Homozygous mutant ES cells were identified by Southern blot analysis and Western blot analysis confirmed the absence of protein product.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations