Allele/Variant

Cacna1dtm1Hssh

Species
Mus musculus
Symbol
Cacna1dtm1Hssh
Category
allele
Allele of gene
Cacna1d
Transgenic Constructs
None
Synonyms
  • alpha(1D)-
  • Cav1.3-
Description
Part of exon 1 and all of exon 2 was replaced with an IRES-BetaGal-polyA-PGK-neo cassette via homologous recombination. Western blot of cerebral membrane fractions and immunohistochemical staining of pancreas sections from homozygous mutant animals did not detect protein product. Unexpectedly, lacZ staining was not detected in mutant animals.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations